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Domi 10mg Suppository

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Domi 10 contains domperidone 10mg, used to relieve nausea, vomiting, and bloating by promoting stomach emptying.
It works by blocking dopamine receptors in the gut and brain, enhancing gastric motility.
Common side effects may include dry mouth, headache, and abdominal cramps; not recommended for long-term use.

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Feature Description
Generic Name Domperidone
Brand Name Domi 10
Strength 10 mg tablet
Drug Class Dopamine (D2) receptor antagonist; prokinetic and antiemetic
Mechanism of Action Blocks dopamine receptors in the gut and chemoreceptor trigger zone, enhancing gastric emptying and reducing nausea
Indications Used for nausea, vomiting, bloating, indigestion, and gastric discomfort
Dosage Usually 10 mg 3 times daily, taken 15–30 minutes before meals; dose may vary by condition
Onset of Action Starts working within 30–60 minutes
Side Effects Dry mouth, headache, abdominal cramps, dizziness, rare risk of irregular heartbeat (especially in elderly)
Warnings Use caution in patients with heart conditions or electrolyte imbalance; avoid long-term use
Contraindications GI bleeding, bowel obstruction, prolactinoma, cardiac arrhythmias, or known allergy to domperidone
Pregnancy & Lactation Use only if clearly needed under doctor’s advice; may pass into breastmilk
Drug Interactions May interact with antifungals, certain antibiotics (erythromycin), and drugs that prolong QT interval
Storage Store below 30°C in a dry place; keep out of reach of children
Prescription Status Prescription-only medicine – to be taken under medical supervision

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