Domi 30mg Suppository
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Domi 30 contains domperidone 30mg, a medication used to relieve nausea, vomiting, and improve gastric motility.
It works by blocking dopamine receptors in the gut and brain, enhancing stomach emptying and reducing nausea.
Common side effects include dry mouth, abdominal cramps, or dizziness; use only under medical supervision.
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| Feature | Description |
|---|---|
| Brand Name | Domi 30 |
| Generic Name | Domperidone |
| Strength | 30 mg tablet |
| Drug Class | Dopamine (D2) receptor antagonist; prokinetic and antiemetic |
| Mechanism of Action | Blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) and upper GI tract, enhancing gastric emptying and reducing nausea/vomiting |
| Indications | Nausea, vomiting, bloating, gastric discomfort, and delayed gastric emptying (gastroparesis) |
| Dosage | Usually taken before meals; dosage varies based on indication and patient’s age/weight |
| Onset of Action | Begins to act within 30–60 minutes |
| Side Effects | Dry mouth, headache, abdominal cramps, dizziness, rarely QT prolongation (cardiac arrhythmia) |
| Warnings | Not recommended for long-term use or high doses due to cardiac risks (especially in elderly) |
| Contraindications | GI bleeding or obstruction, prolactin-releasing tumors, severe liver dysfunction |
| Pregnancy & Lactation | Use only if prescribed and necessary; may pass into breast milk |
| Drug Interactions | Avoid with drugs that prolong QT interval (e.g., erythromycin, ketoconazole) or CYP3A4 inhibitors |
| Storage | Store at room temperature below 30°C, away from moisture and light |
| Prescription Status | Prescription-only medicine – must be used under medical supervision |
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