DuoTrav Drop

What is DuoTrav?

DuoTrav is a prescription eye drop used to lower raised pressure in the eyes, particularly in patients with:

• Open-angle glaucoma

• Ocular hypertension

It is used when a single medication isn’t enough to control the pressure.

Active Ingredients

Each mL contains:

• Travoprost 0.004% – a prostaglandin analog

• Timolol 0.5% – a non-selective beta-blocker

Together, they work by:

• Travoprost: Increases the outflow of fluid from the eye.

• Timolol: Decreases the production of fluid inside the eye.

Dosage and Administration

• One drop in the affected eye once daily, preferably at the same time each day (morning or evening).

• Do not use more than once daily, as overuse may reduce effectiveness.

• Remove contact lenses before application and wait at least 15 minutes before reinserting them.

• If using other eye drops, wait at least 5 minutes between each medication.

Who Should Not Use It

Avoid DuoTrav if you:

• Are allergic to travoprost, timolol, or any of the ingredients.

• Have a history of asthma or other severe breathing disorders like COPD.

• Have serious heart problems such as slow heart rate, heart block, or heart failure.

Possible Side Effects

Common eye-related side effects:

• Redness

• Itching or burning

• Blurred vision

• Eye pain

• Increased eyelash growth

• Darkening of the eyelid or iris (may be permanent)

Systemic (whole-body) side effects from timolol:

• Slow heartbeat

• Low blood pressure

• Fatigue or dizziness

• Shortness of breath (especially in asthma patients)

Precautions

• Use with caution in diabetics, as timolol may mask signs of low blood sugar.

• Should not be used during pregnancy unless necessary.

• Not recommended during breastfeeding unless advised by a doctor.

• Use with care in elderly patients and those with other medical conditions.

Storage

• Store below 25°C.

• Do not freeze.

• Discard 4 weeks after opening the bottle to avoid contamination.

Benefits

• Combines two effective agents in one bottle, simplifying treatment.

• Requires only one daily dose.

• Shown to effectively lower intraocular pressure by 30–40%.