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Primolut N (Norethisterone 5 mg Tablets)

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Primolut N is a prescription progestin (norethisterone 5 mg) used to regulate periods, treat PMS, endometriosis, heavy bleeding, and delay menstruation.
Common side effects include spotting, bloating, mood changes, and breast tenderness; serious risks include blood clots, liver issues, and vision changes.
Use under medical supervision, especially in patients with cardiovascular risk factors, smokers, or those on interacting medications.

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Name:

Primolut N (Norethisterone 5 mg Tablets)


Category:

Hormonal Therapy / Progestin


Prescription Status:

Prescription Only Medicine (POM)


Main Ingredient:

  • Norethisterone 5 mg
    (A synthetic form of the hormone progesterone)


Uses:

  • To regulate menstrual cycles

  • Treats heavy or painful periods

  • Used for premenstrual syndrome (PMS)

  • Treats endometriosis

  • Helps to delay menstruation for special events

  • Manages dysfunctional uterine bleeding


Dosage: (As prescribed by a doctor)

  • For period delay: 5 mg three times daily, starting 3 days before expected period, for up to 14 days

  • For menstrual disorders: 5 mg 2–3 times daily, from day 16 to 25 of the cycle

  • For endometriosis: Start with 5 mg twice daily, may increase to 10 mg twice daily, for 4–6 months


How It Works:

Norethisterone mimics the natural hormone progesterone, helping to stabilize the uterine lining, delay ovulation, and prevent abnormal bleeding.


Common Side Effects:

  • Bloating, nausea, or stomach discomfort

  • Breast tenderness, acne, or headache

  • Mood changes, irritability, or tiredness

  • Weight gain or water retention


Serious Side Effects / Precautions:

  • Blood clots (signs: leg pain, chest pain, shortness of breath)

  • Liver issues (jaundice, pain under ribs)

  • Vision changes, speech disturbance, or migraine aura

  • Should NOT be used in:

    • Pregnancy or breastfeeding

    • History of blood clots or stroke

    • Severe liver disease

    • Uncontrolled high blood pressure

    • Known hormone-sensitive cancers


Warnings:

  • Stop medication 4 weeks before surgery

  • Use with caution in smokers, diabetics, or those with depression

  • Avoid alcohol and certain enzyme-inducing medications which may reduce effectiveness

  • Not a contraceptive unless used as part of a birth control plan

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