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Amoxicillin 500 mg Capsule (Local Brand)

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Amoxicillin 500 mg capsules are a broad-spectrum antibiotic used to treat respiratory, urinary, skin, and dental infections. They are taken orally, usually every 8 to 12 hours, with or without food. Use with caution in allergic patients and those with kidney problems.

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Product Overview
Each capsule contains 500 mg of amoxicillin, a broad-spectrum penicillin antibiotic effective against many bacterial infections.
Capsules are typically hard gelatin, often colored (e.g., red and yellow), designed for oral use.
Commonly supplied in bottles or blister packs for outpatient treatment.


Indications
Used to treat:

  • Respiratory infections such as bronchitis, pneumonia, and tonsillitis

  • Ear, nose, and throat infections like sinusitis and otitis media

  • Urinary tract infections

  • Skin and soft tissue infections

  • Dental infections


Dosage and Administration

  • Adults and children over 40 kg: 500 mg every 8 hours or 1 g every 12 hours based on severity.

  • Children under 40 kg: dosing usually based on weight with oral suspensions preferred.

  • Capsules can be taken with or without food; food may reduce stomach upset.

  • Complete full course to avoid resistance.


Contraindications and Precautions

  • Avoid in patients allergic to penicillins or beta-lactam antibiotics.

  • Use cautiously in patients with renal impairment; dose adjustments may be necessary.

  • Monitor for allergic reactions during therapy.


Side Effects
Common:

  • Nausea, vomiting, diarrhea, rash
    Rare but serious:

  • Severe allergic reactions including anaphylaxis

  • Antibiotic-associated colitis

  • Liver enzyme abnormalities (rare)


Mechanism of Action
Amoxicillin inhibits bacterial cell wall synthesis, leading to bacterial death. It targets many gram-positive and some gram-negative bacteria.


Storage
Store below 25 degrees Celsius in a dry place. Protect from moisture and light. Keep out of reach of children.

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