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Ceftriaxone Injection 1g
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Ceftriaxone 1g injection is a prescription-only cephalosporin antibiotic used to treat severe bacterial infections like pneumonia, meningitis, and sepsis. It works by inhibiting bacterial cell wall synthesis. Common side effects include injection site pain, diarrhea, and rash.
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| Category | Details |
|---|
| Generic Name | Ceftriaxone |
| Brand Name | Rocephin, Cefaxone |
| Drug Class | Cephalosporin (antibiotic) |
| Dosage Form | Injection (1g vial) |
| Strength Available | 1g vial |
| Indications | – Severe bacterial infections (e.g., meningitis, pneumonia, sepsis, UTI) |
| – Infections of the skin, bones, joints, and soft tissue |
| Mechanism of Action | Inhibits bacterial cell wall synthesis, leading to bacterial cell death |
| Usual Dose | 1-2 g once daily (depending on infection) |
| Onset of Action | 1–2 hours |
| Half-life | 6–9 hours |
| Metabolism | Hepatic (liver) |
| Excretion | Primarily in urine |
| Common Side Effects | – Pain or swelling at injection site |
| – Diarrhea, rash, nausea |
| Serious Adverse Effects | – Allergic reactions (e.g., anaphylaxis) |
| – Superinfection (e.g., C. difficile) |
| – Hemolytic anemia, jaundice |
| Contraindications | – Known hypersensitivity to ceftriaxone or other cephalosporins |
| Drug Interactions | – Calcium-containing IV solutions (precipitation risk) |
| Pregnancy Category | B (generally considered safe) |
| Prescription Status | Prescription Only |
| Storage Conditions | Store in a cool, dry place, protect from light; reconstituted solution should be refrigerated |
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