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Cefuroxime Suspension
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Cefuroxime suspension is a prescription-only antibiotic used to treat bacterial infections like respiratory tract infections and otitis media. It works by inhibiting bacterial cell wall synthesis. Common side effects include diarrhea, rash, and nausea.
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| Category | Details |
|---|---|
| Generic Name | Cefuroxime |
| Brand Name | Enacef , Kefrox , among others |
| Drug Class | Cephalosporin (antibiotic) |
| Dosage Form | Oral suspension |
| Strength Available | 125 mg/5 mL, 250 mg/5 mL |
| Indications | – Bacterial infections (e.g., upper respiratory tract infections, otitis media) |
| – Sinusitis, skin infections, and urinary tract infections | |
| Mechanism of Action | Inhibits bacterial cell wall synthesis, causing bacterial cell death |
| Usual Dose (Children) | 10-15 mg/kg/day, divided into 2 doses |
| Usual Dose (Adults) | 250 mg to 500 mg twice daily for infections |
| Onset of Action | 1–2 hours |
| Half-life | 1–2 hours |
| Metabolism | Hepatic (liver) |
| Excretion | Primarily in urine |
| Common Side Effects | – Diarrhea, nausea |
| – Rash, headache, abdominal pain | |
| Serious Adverse Effects | – Allergic reactions (e.g., anaphylaxis) |
| – Superinfection, liver damage | |
| Contraindications | – Known hypersensitivity to cefuroxime or other cephalosporins |
| Drug Interactions | – Antacids (reduce absorption) |
| Pregnancy Category | B (generally considered safe) |
| Prescription Status | Prescription Only |
| Storage Conditions | Store at room temperature, protect from light; refrigerate after reconstitution |
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