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Amoksiklav tablet 1g

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Amoksiklav 1g tablet contains 875 mg amoxicillin and 125 mg clavulanic acid, used to treat bacterial infections like respiratory, urinary, and skin infections.
It works by inhibiting bacterial cell wall synthesis and blocking beta-lactamase enzymes.
Typical dose is one tablet every 12 hours; common side effects include diarrhea and nausea.

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Brand Name: Amoksiklav
Generic Name: Amoxicillin + Clavulanic Acid
Formulation: Film-coated tablet
Strength: 1000 mg (875 mg Amoxicillin + 125 mg Clavulanic Acid)


Composition:

  • Amoxicillin (as trihydrate): 875 mg
  • Clavulanic acid (as potassium clavulanate): 125 mg

Appearance:

  • Oblong or oval, white to off-white, film-coated tablet
  • May have score line or brand markings depending on the manufacturer

Pharmacological Class:

  • Antibiotic (Beta-lactam / Beta-lactamase inhibitor combination)

Mechanism of Action:

  • Amoxicillin: A penicillin-type antibiotic that inhibits bacterial cell wall synthesis.
  • Clavulanic acid: Inhibits beta-lactamase enzymes produced by resistant bacteria, enhancing amoxicillin’s effect.

Indications:

  • Respiratory tract infections (e.g. sinusitis, pneumonia, bronchitis)
  • Urinary tract infections
  • Skin and soft tissue infections
  • Dental infections
  • Bone and joint infections

Dosage (Typical Adult):

  • 1 tablet every 12 hours, or as directed by a healthcare provider
  • Duration: Usually 5–14 days depending on severity and type of infection

Side Effects:

  • Common: Diarrhea, nausea, skin rash
  • Less common: Liver enzyme elevation, fungal infections (e.g., thrush)
  • Rare: Anaphylaxis, Stevens-Johnson syndrome, severe colitis

Contraindications:

  • Hypersensitivity to penicillins, cephalosporins, or beta-lactam antibiotics
  • History of amoxicillin-clavulanate-associated jaundice or hepatic dysfunction

Precautions:

  • Use with caution in patients with hepatic or renal impairment
  • Monitor liver function during prolonged therapy
  • Can affect oral contraceptive effectiveness

Storage:

  • Store below 25°C
  • Protect from moisture and light
  • Keep out of reach of children

Note:

Always complete the full course even if symptoms improve. Misuse or incomplete therapy can lead to resistance.

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