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Amoxicillin 500 mg Capsule (UK Generic)

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Amoxicillin 500 mg capsules are a broad-spectrum antibiotic used to treat various bacterial infections like respiratory, urinary, and skin infections. They are taken orally, usually every 8 to 12 hours, with or without food. Use cautiously in allergic patients and those with kidney issues.

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Product Overview
Each capsule contains 500 mg of amoxicillin trihydrate, a broad-spectrum penicillin antibiotic.
Capsules are typically hard gelatin, white or pale yellow, designed for oral use.
Available in blister packs or bottles for treating various bacterial infections.


Indications
Used to treat:

  • Respiratory tract infections such as bronchitis, tonsillitis, and pneumonia

  • Ear, nose, and throat infections including otitis media and sinusitis

  • Urinary tract infections

  • Skin and soft tissue infections

  • Dental infections

  • Part of combination therapy for Helicobacter pylori eradication


Dosage and Administration

  • Adults and children over 40 kg: 500 mg every 8 hours or 1 g every 12 hours, depending on severity.

  • Children under 40 kg: Use weight-based dosing with oral suspensions instead of capsules.

  • Capsules can be taken with or without food; taking with food may reduce stomach upset.

  • Complete the full prescribed course to avoid resistance.


Contraindications and Precautions

  • Contraindicated in patients allergic to penicillins or beta-lactams.

  • Use cautiously in patients with renal impairment; adjust doses accordingly.

  • Monitor for allergic reactions during treatment.


Side Effects
Common side effects:

  • Nausea, vomiting, diarrhea, rash
    Rare serious side effects:

  • Severe allergic reactions, including anaphylaxis

  • Clostridium difficile-associated diarrhea

  • Liver enzyme abnormalities (rare)


Mechanism of Action
Amoxicillin disrupts bacterial cell wall synthesis, causing bacterial death. Effective against many gram-positive and some gram-negative bacteria.


Storage
Store capsules at room temperature below 25 degrees Celsius. Protect from moisture and light. Keep out of reach of children.

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