Cefixime Suspension

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Cefixime suspension is a prescription-only antibiotic used to treat bacterial infections like ear, respiratory, and urinary tract infections. It works by inhibiting bacterial cell wall synthesis. Common side effects include diarrhea, nausea, and abdominal pain.

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Category	Details
Generic Name	Cefixime
Brand Name	Suprax (suspension form)
Drug Class	Cephalosporin (antibiotic)
Dosage Form	Oral suspension
Strengths Available	100 mg/5 mL, 200 mg/5 mL
Indications	– Bacterial infections (e.g., ear infections, respiratory, urinary tract)
	– Gonorrhea
Mechanism of Action	Inhibits bacterial cell wall synthesis, leading to bacterial cell death
Usual Pediatric Dose	– 8 mg/kg/day, divided into 1-2 doses depending on infection
	– Max dose: 400 mg/day
Usual Adult Dose	200 mg to 400 mg daily in divided doses
Onset of Action	1-2 hours
Half-life	3-4 hours
Metabolism	Hepatic (liver)
Excretion	Primarily in urine
Common Side Effects	– Diarrhea, nausea
	– Abdominal pain, rash
Serious Adverse Effects	– Allergic reactions (rash, anaphylaxis)
	– Liver damage, blood dyscrasias
Contraindications	– Known hypersensitivity to cephalosporins or penicillins
Drug Interactions	– Antacids (reduce absorption), other antibiotics
Pregnancy Category	B (considered safe during pregnancy)
Prescription Status	Prescription Only
Storage Conditions	Store in a cool, dry place; refrigerate after reconstitution, discard after 14 days