Water for Injection

Form: Sterile, non-pyrogenic water
Category: Pharmaceutical solvent

Indications

• Used as a solvent or diluent for the preparation of parenteral (injectable) solutions, such as reconstituting antibiotics, vitamins, or other injectable medications

• Not intended for direct intravenous injection unless adequately diluted with a solute to make it isotonic

Composition

• Contains only sterile, purified water

• Free from any antimicrobial agents or other added substances

• Must meet strict pharmacopeia standards (e.g., BP, USP) for purity, sterility, and endotoxin levels

Dosage & Administration

• Volume depends on the specific medication being prepared

• Route of administration (IM, IV, SC, etc.) is determined by the medication it is mixed with

• For single use only; any unused portion should be discarded

Precautions

• Do not inject directly without solute—pure water can cause hemolysis (destruction of red blood cells) if given IV

• Use aseptic technique to avoid contamination

• Do not use if the solution is cloudy or contains particles

Storage

• Store at 15–30°C

• Protect from freezing and contamination

• Use immediately after opening

Advice to Healthcare Professionals

• Always check compatibility with the drug being reconstituted

• Label prepared solutions clearly with drug name, concentration, and expiration time

• Use WFI from sealed ampoules or vials to maintain sterility